Soothe your dog's anxiety with on-the-go Adaptil Calming Pheromone Spray. Safe for dogs of all ages and ideal for new environments, loud noises (think: thunder, lightning), travel, and vet visits. Adaptil helps your dog feel calm and comfortable by mimicking a mother’s natural nursing pheromones. Each application lasts 4-5 hours and can be sprayed in the car, on collars, shirts, leashes, bandanas, blankets, crates, and more (do not spray directly on dog).